OMICS 4.0



The major aim of the OMICS 4.0 project is to integrate existing metabolomics, proteomics, transcriptomics and genomics activities at the Campus Technopol Tulln. The project intends to establish a bioinformatics platform to promote collaborations among the various research groups being active in the respecive OMICS disciplines.


News


Virtual meetings
(March-July 2020)

The project work continued during the COVID-10 pandemic as bioinformatics work can be carried out remotely and via virtual meetings.


11th of April 2019

On the 11th of April 2019 Justin JJ. van der Hooft has been invided to present his ground-breaking work on substructure motif discovery using the developed MS2LDA platform. For further details see the official announcement.


12th of December 2018

On the 12th December 2018 our kickoff-meeting will take place at the UFT-Tulln.


1st of June 2023

On the 1st June 2023 the Data 4 Omics Symposium took place. Please find further information about the conference organized in the course of the OMICS4.0 project at metabolomics-ifa.boku.ac.at/Data4Omics_Symposium.


October 2018

Applied bioinformatics for life-science research


The OMICS 4.0 project is a dedicated bioinformatics project involving 4 research groups situated at the University of Natural Resources, Vienna (Location IFA-Tulln), the University of Applied Sciences, FH Wiener Neustadt, Campus Tulln and the Austrian Institute of Technology, Campus UFT Tulln.

To be able to meet the challenges of the fast developing OMICS-technologies and to ensure adequate handling of the associated, steadily increasing amount of data, novel algorithms and bioinformatics tools are indispensable.

The major aim of the OMICS 4.0 project is to integrate existing metabolomics, proteomics, transcriptomics and genomics activities at the Campus Technopol Tulln. The project intends to establish a bioinformatics platform to promote collaborations among the various research groups being active in the respective OMICS disciplines.

The project is structured in four scientific modules (see below), all of which intend to develop novel, customized bioinformatics tools for processing, statistical evaluation, visualization and interpretation of analytical raw data. To maximize the benefit of the tools to be developed, each of the bioinformatics research fellows (PhD students and Postdocs) will be fully integrated into a specific ongoing life science project, addressing defined biological research questions. For each of these associated projects, defined user-friendly software packages shall be developed.

The OMICS 4.0 project started on the 1st of October 2018 and will last for four years

Project modules



Publications

  • Ćeranić A, Bueschl C, Doppler M, Parich A, Xu K, Lemmens M, Buerstmayr H, Schuhmacher R (2020) Enhanced Metabolome Coverage and Evaluation of Matrix Effects by the Use of Experimental-Condition-Matched 13C-Labeled Biological Samples in Isotope-Assisted LC-HRMS Metabolomics. Metabolites 2020, 10, 434. doi: 10.3390/metabo10110434

  • Doppler M, Kluger B, Bueschl C, Steiner B, Buerstmayr H, Lemmens M, Krska R, Adam G and Schuhmacher R (2019) Stable Isotope-Assisted Plant Metabolomics: Investigation of Phenylalanine-Related Metabolic Response in Wheat Upon Treatment With the Fusarium Virulence Factor Deoxynivalenol. Front. Plant Sci. 10:1137. doi: 10.3389/fpls.2019.01137

  • Doppler M, Bueschl C, Kluger B, Koutnik A, Lemmens M, Buerstmayr H, Rechthaler J, Krska R, Adam G and Schuhmacher R (2019) Stable Isotope–Assisted Plant Metabolomics: Combination of Global and Tracer-Based Labeling for Enhanced Untargeted Profiling and Compound Annotation. Front. Plant Sci. 10:1366. doi: 10.3389/fpls.2019.01366

  • Flasch M, Bueschl C, Woelflingseder L, Schwartz-Zimmernamm HE, Adam G, Schuhmacher R, Marko D, Warth B (2020) Stable Isotope-Assisted Metabolomics for deciperhing Xenobiotic Metabolism in Mammalian Cell Culture. ACS Chemical Biology. 15, 4, 970-981. doi: 1.01021/acschembio.9b01016



Funding agency


Gefördert durch das Land Niederösterreich.
Funding for this project has been kindly provided by the Office of the Provincial Government of Lower Austria.

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+43 1 47654-97304






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